Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Products By Taro Noguchi
English | PDF,EPUB | 2017 (2018 Edition) | 89 Pages | ISBN : 9811066221 | 6.29 MB
This thesis mainly describes the development of a screening process for a mirror-image library of chiral natural products. It demonstrates how, by using mirror-image proteins for the screening of available natural products, unavailable mirror-image isomers of natural products can be screened in a mirror process. Moreover, as mirror-image isomers including target proteins and natural products are mainly prepared by means of chemical synthesis, the screening strategy presented here suggests the importance of organic chemistry.